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Secondary mitochondrial dysfunction Acquired dysfunction may develop from oxidative stress, inflammation, nutrient deficiency, medication toxicity, toxic exposure, aging, metabolic disease, infection, poor sleep, inactivity or chronic illness

One important limitation: the clinical weight loss results were modest

2020;7(10): ofaa437

Potential Benefits of BPC-157 Based on preclinical data, BPC-157 is being studied for multiple therapeutic applications

Hydropersulfides are thought to mediate many of the antioxidant signaling functions once ascribed purely to hydrogen sulfide via modification of protein cysteine (Cys) residues in a process referred to as persulfidation